Search on: P53 TUMOR SUPPRESSOR PROTEIN 
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Descriptor English:   Tumor Suppressor Protein p53 
Descriptor Spanish:   Proteína p53 Supresora de Tumor 
Descriptor Portuguese:   Proteína Supressora de Tumor p53 
Synonyms English:   Cellular Tumor Antigen p53
Oncoprotein p53
Phosphoprotein, pp53
TP53 Protein
TRP53 Protein
p53 Antigen
p53 Tumor Suppressor Protein
pp53 Phosphoprotein  
Tree Number:   D12.776.157.687.650
D12.776.260.820
D12.776.624.776.775
D12.776.660.720.650
D12.776.744.845
Definition English:   Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER. 
History Note English:   2005(1991); 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29089 
Unique Identifier:   D016159 

Occurrence in VHL:
 

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